This course manual is available in English and contains three parts. The first two sections are a combined 69 pages in length, and the last section is 126 pages in length. The intended audience includes: educational institutions, ministries and technical assistance agencies, heath care and public health professionals, as well as environmental health specialists. This course is appropriate for any development context; water resources development is used as the illustrative contextual example. This manual presents in detail the principles of problem-based learning for the development of professional capacities to deal with issues of an intersectoral nature. Part of the Manual is a practical, step-by-step guide on how to organize the course, in the context of one particular field of work, Health Impact Assessment of development projects. Preparations for and implementation of a task-oriented course are illustrated from the experience of five courses held in different parts of the world. The third part contains all course materials, including the Task Guides, guides for tutors and resource persons, generic course schedules and instructions for field trips.